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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
14.24
Human Site:
Y484
Identified Species:
26.11
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
Y484
K
K
H
I
Q
R
D
Y
Y
N
T
L
L
Q
T
Chimpanzee
Pan troglodytes
XP_513987
742
82925
Y484
K
K
H
I
Q
R
D
Y
Y
N
T
L
L
Q
T
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
Y484
K
K
H
I
Q
R
D
Y
Y
N
T
L
L
Q
T
Dog
Lupus familis
XP_537198
743
82483
Y484
K
Q
I
Q
R
D
C
Y
N
T
L
L
Q
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
Y484
K
R
I
Q
E
E
C
Y
S
S
L
S
Q
T
G
Rat
Rattus norvegicus
Q5M9F8
807
89107
P518
L
C
G
L
T
V
D
P
E
K
S
V
R
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
A1109
G
D
R
A
P
P
G
A
R
G
G
A
A
P
A
Chicken
Gallus gallus
NP_001012613
698
77220
P464
S
L
T
T
S
E
K
P
A
E
E
W
P
D
W
Frog
Xenopus laevis
Q561M0
827
91284
S575
T
G
V
S
S
L
T
S
K
F
I
R
T
G
G
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
T485
S
F
Q
A
A
E
N
T
T
S
E
H
I
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
T451
S
I
S
P
L
M
N
T
R
S
F
D
V
E
D
Honey Bee
Apis mellifera
XP_001123124
613
70111
L382
D
E
L
K
S
Q
I
L
P
E
L
L
V
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
E496
K
L
E
V
E
E
E
E
T
S
S
E
T
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
100
100
20
N.A.
13.3
6.6
N.A.
0
0
0
0
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
26.6
N.A.
0
0
0
20
N.A.
26.6
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
8
0
0
8
8
0
0
8
8
0
8
% A
% Cys:
0
8
0
0
0
0
16
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
31
0
0
0
0
8
0
16
8
% D
% Glu:
0
8
8
0
16
31
8
8
8
16
16
8
0
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
8
0
0
8
8
0
0
24
24
% G
% His:
0
0
24
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
16
24
0
0
8
0
0
0
8
0
8
0
8
% I
% Lys:
47
24
0
8
0
0
8
0
8
8
0
0
0
0
0
% K
% Leu:
8
16
8
8
8
8
0
8
0
0
24
39
24
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
8
24
0
0
0
0
0
% N
% Pro:
0
0
0
8
8
8
0
16
8
0
0
0
8
8
0
% P
% Gln:
0
8
8
16
24
8
0
0
0
0
0
0
16
24
8
% Q
% Arg:
0
8
8
0
8
24
0
0
16
0
0
8
8
0
0
% R
% Ser:
24
0
8
8
24
0
0
8
8
31
16
8
0
8
0
% S
% Thr:
8
0
8
8
8
0
8
16
16
8
24
0
16
16
24
% T
% Val:
0
0
8
8
0
8
0
0
0
0
0
8
16
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
39
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _